Prostate Health Index Literature
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Clinical Use of [-2]proPSA (p2PSA) and Its Derivatives (%p2PSA and Prostate Health Index) for the Detection of Prostate Cancer: A Review of the Literature
Prostate-specific antigen (PSA) is recognized as an organ-specific marker with low specificity and sensitivity in discriminating prostate cancer (PCa) from other benign conditions, such as prostatic hyperplasia or chronic prostatitis. Thus, in the case of clinical suspicion, a PCa diagnosis cannot be made without a prostate biopsy. [-2]proPSA (p2PSA), a precursor of PSA, has been investigated a...
متن کاملSerum index test %[-2]proPSA and Prostate Health Index are more accurate than prostate specific antigen and %fPSA in predicting a positive repeat prostate biopsy.
PURPOSE We tested the hypothesis that serum isoform [-2]proPSA derivatives %p2PSA and Prostate Health Index are accurate predictors of prostate cancer in men scheduled for repeat biopsy. MATERIALS AND METHODS The study was an observational prospective evaluation of a clinical cohort of men with 1 or 2 previous negative prostate biopsies, with persistent suspicion of prostate cancer. They were...
متن کاملInformation Seeking Behavior versus Scientific Publication Behavior: An infodemiological study on prostate cancer
Background and Aim: The current study aimed to investigate the state of health information supply and demand on prostate cancer among Iranian medical researchers and Iranian web users during 2011 to 2015. The purpose of this study, based on infodemiology indicators, was to investigate the alignment of health information supply and demand on prostate cancer among Iranian medical researchers and ...
متن کامل[The practical application of marker -2proPSA and health index of prostate phi in diagnostics of prostate cancer].
The article demonstrates that prostate-specific antigen (PSA) has some limitations in detection of cancer of prostate. It was demonstrated that isoform of free PSA - 2proPSA has higher specificity in comparison with total PSA (tPSA) and percentage tPSA and free PSA (%free PSA) in detection of cancer of prostate. The application of Prostate Health Index including such indicators as -2PSA, free P...
متن کاملElevated Prostate Health Index (phi) and Biopsy Reclassification During Active Surveillance of Prostate Cancer
The Prostate Health Index (phi) has been FDA approved for decision-making regarding prostate biopsy. Phi has additionally been shown to positively correlate with tumor volume, extraprostatic disease and higher Gleason grade tumors. Here we describe a case in which an elevated phi encouraged biopsy of a gentleman undergoing active surveillance leading to reclassification of his disease as high r...
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تاریخ انتشار 2013